Biotechnologist, Mammalian Manufacturing - Small Scale Operations
Lonza
- Tuas, Singapore
- Permanent
- Full-time
- Learn and perform well-defined procedures within a GMP manufacturing setting
- Perform equipment monitoring & and basic 6S housekeeping
- Perform basic laboratory tasks (e.g. sampling, pH/ conductivity/ osmolality measurements etc.)
- Perform routine sanitization tasks to maintain facility standards
- Trained & signed off on Performance Measures (PMs) relating to CIP/ SIP/ basic tank & instrument operations
- Demonstrate aseptic technique in the handling of product/ materials
- Perform basic process & equipment troubleshooting
- Multi-task on equipment preparations & operations to ensure adherence to schedule
- Attain full competency in the performance of all operations relevant to manufacturing areas assigned.
- Display basic process & equipment troubleshooting ability under routine scenarios.
- Become a technical process expert by exhibiting basic understanding of critical process/operational parameters and target/acceptable ranges, as well as interactions between different process parameters.
- Use Standard Operating Procedures (SOPs), logbooks & Batch Records (BRs) effectively & competently
- Submit samples via Laboratory Information Management System (LIMS)
- Skill and knowledge of aseptic technique for subculture stages example using culture flask, spinners, wave bioreactors, etc.
- Technical knowledge on the bioreactor culture control example pH/DO control, CO2/O2 control, cell performance, and metabolites analysis.
- Skill and knowledge of column chromatography techniques, tangential flow filtration techniques, micro/Nano filtration techniques, pH/Conductivity adjustment techniques, aseptic techniques.
- Technical knowledge on the chromatography operating interface example using UNICORN software and various DeltaV control parameters for chromatography and UF operation.
- Knowledge in single use applications for the respective processes.
- Degree/Diploma in a related Science/Engineering discipline
- Some relevant work experience in a similar manufacturing industry or cleanroom environment
- Knowledge of Biopharmaceutical processing is an added asset
- Knowledge of cGMP applications
- Positive team oriented attitude
- Strong communication and interpersonal skills
- Willing to perform rotating 12-hour shift pattern